The workplace is an important setting for efforts to improve health and well-being because it provides access to large numbers of workers, existing social networks to reach workers, resources to implement initiatives for change, and the opportunity for ongoing, long-term support. However, research conducted to assess the effectiveness of corporate wellness programs has generated mixed results. Whereas some welldesigned randomized trials (e.g., Haufe et al., 2019; Wang et al., 2020) and systematic reviews (e.g., Hulls et al., 2022) show positive and meaningful impacts, other rigorously designed experimental trials (e.g., Song & Baicker, 2019) or meta-analytic results (e.g., Rongen et al., 2013) show limited health or economic outcomes. To increase the likelihood for successful outcomes, it is important to understand what factors related to work site health programs drive improvements (Goetzel & Pronk, 2010; Hulls et al., 2022; Pronk, 2020). For example, work site health programs that show positive outcomes tend to be comprehensive, integrated, build iteratively over time (longer duration), incorporate best practices by design, focus on outcomes that are aligned with business goals and employee needs (including target populations), depend on delivery, industry, and outcome, and have accountable leadership and dedicated staff to ensure optimal implementation and evaluation for continuous improvement (Goetzel et al., 2014; Hulls et al., 2022; Pronk, 2014, 2020; Robroek et al., 2020; Soler et al., 2010). Similarly, it is important to ensure that programs designed to improve the health and well-being of workers are properly positioned in the context of their local environment so they can generate scalable, sustainable, and equitable results.