The Roundtable on Obesity Solutions of the Health and Medicine Division of the National Academies of Sciences, Engineering, and Medicine held a workshop in Washington, DC, on September 27, 2016, titled “Driving Action and Progress on Obesity Prevention and Treatment.” The workshop was designed to (1) review the progress that has been made in obesity prevention and treatment; (2) identify some of the levers that can drive significant future progress; and (3) discuss how gaps in the field can be filled. This Proceedings of a Workshop—in Brief highlights key points made during the presentations and discussions and is not intended to provide a comprehensive summary of information shared during the workshop. The information and suggestions for future action summarized here reflect the knowledge and opinions of individual workshop participants and should not be seen as the consensus of the workshop, Roundtable on Obesity Solutions, or the National Academies of Sciences, Engineering, and Medicine.