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L. Gattinoni All authors
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Publications While At HealthPartners
selected publications
Journal Article
  • Mechanical power ratio threshold for ventilator-induced lung injury. 
    Intensive care medicine experimental. 2024
  • High- versus low-flow extracorporeal respiratory support in experimental hypoxemic acute lung injury. 
    American Journal of Respiratory and Critical Care Medicine. 2023
  • Ventilatory ratio, dead space, and venous admixture in patients with acute respiratory distress syndrome. 
    British Journal of Anaesthesia. 2023
  • End-tidal to arterial Pco(2) ratio as guide to weaning from venovenous extracorporeal membrane oxygenation. 
    American Journal of Respiratory and Critical Care Medicine. 2022
  • Energy dissipation during expiration and ventilator-induced lung injury: an experimental animal study. 
    Journal of applied physiology (Bethesda, Md.. 2022
  • Intracycle power distribution in a heterogeneous multi-compartmental mathematical model: possible links to strain and VILI. 
    Intensive care medicine experimental. 2022
  • Mechanical power thresholds during mechanical ventilation: an experimental study. 
    Physiological reports. 2022
  • Mechanisms of oxygenation responses to proning and recruitment in COVID-19 pneumonia. 
    Intensive Care Medicine. 2022
  • Paradoxical positioning: does "head up" always improve mechanics and lung protection?. 
    Critical Care Medicine. 2022
  • Paradoxical response to chest wall loading predicts a favorable mechanical response to reduction in tidal volume or PEEP. 
    Critical Care (London, England). 2022
  • Intra-cycle power: is the flow profile a neglected component of lung protection?. 
    Intensive Care Medicine. 2021
  • Intracycle power and ventilation mode as potential contributors to ventilator-induced lung injury. 
    Intensive care medicine experimental. 2021
  • Prevalence and outcome of silent hypoxemia in COVID-19. 
    Minerva Anestesiologica. 2021
  • Role of total lung stress on the progression of early COVID-19 pneumonia. 
    Intensive Care Medicine. 2021
  • "Less is More" in mechanical ventilation. 
    Intensive Care Medicine. 2020
  • Does iso-mechanical power lead to iso-lung damage: an experimental study in a porcine model. 
    Anesthesiology. 2020
  • Estimating the damaging power of high-stress ventilation. 
    Respiratory Care. 2020
  • Management of COVID-19 respiratory distress. 
    JAMA. 2020
  • Physiological and quantitative CT-scan characterization of COVID-19 and typical ARDS: a matched cohort study. 
    Intensive Care Medicine. 2020
  • Time course of evolving ventilator-induced lung injury: the "shrinking baby lung". 
    Critical Care Medicine. 2020
  • Positive end-expiratory pressure and mechanical power. 
    Anesthesiology. 2019
  • Understanding lactatemia in human sepsis. Potential impact for early management. 
    American Journal of Respiratory and Critical Care Medicine. 2019
  • Energetics and the root mechanical cause for ventilator-induced lung injury. 
    Anesthesiology. 2018
  • Positional effects on the distributions of ventilation and end-expiratory gas volume in the asymmetric chest-a quantitative lung computed tomographic analysis. 
    Intensive care medicine experimental. 2018
  • Protecting the ventilated lung: vascular surge and deflation energetics. 
    American Journal of Respiratory and Critical Care Medicine. 2018
  • Evidence or belief-based medicine? Ten doubts. 
    Intensive Care Medicine. 2017
  • Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome. 
    American Journal of Respiratory and Critical Care Medicine. 2008
  • Ventilatory management of acute respiratory distress syndrome: a consensus of two. 
    Critical Care Medicine. 2004
    • Editorial Article
  • In search of the Holy Grail: identifying the best PEEP in ventilated patients [editorial]. 
    Intensive Care Medicine.  48. 2022
  • Prone position and COVID-19: mechanisms and effects [editorial]. 
    Critical Care Medicine.  50. 2022
  • "Established" respiratory treatment in acute respiratory distress syndrome: scientific rigor or a square peg in a round hole [editorial]?. 
    American Journal of Respiratory and Critical Care Medicine.  203. 2021
  • COVID-19 and ARDS: the baby lung size matters [editorial]. 
    Intensive Care Medicine.  47. 2021
  • Complexity and unanswered questions in the pathophysiology of COVID-19 ARDS [editorial]. 
    Intensive Care Medicine.  47. 2021
  • Conceptual simplicity in pursuit of precision [editorial]. 
    Intensive Care Medicine.  47. 2021
  • Isn't it time to abandon ARDS? The COVID-19 lesson [editorial]. 
    Critical Care (London, England).  25. 2021
  • Pathophysiology of COVID-19-associated acute respiratory distress syndrome [editorial]. 
    The Lancet. Respiratory medicine.  9. 2021
  • Reply to Tobin: Respiratory drive measurements do not signify conjectural patient self-inflicted lung injury [editorial]. 
    American Journal of Respiratory and Critical Care Medicine.  203. 2021
  • The 4DPRR Index and mechanical power: a step ahead or four steps backward [editorial]?. 
    American Journal of Respiratory and Critical Care Medicine.  204. 2021
  • COVID-19 phenotypes: leading or misleading [editorial]?. 
    European Respiratory Journal.  56. 2020
  • COVID-19: scientific reasoning, pragmatism and emotional bias [editorial]. 
    Annals of intensive care.  10. 2020
  • Recruiting the acutely injured lung: how and why [editorial]?. 
    American Journal of Respiratory and Critical Care Medicine.  201. 2020
  • Spontaneous breathing, transpulmonary pressure and mathematical trickery [editorial]. 
    Annals of intensive care.  10. 2020
  • The baby lung and the COVID-19 era [editorial]. 
    Intensive Care Medicine.  46. 2020
  • The respiratory drive: an overlooked tile of COVID-19 pathophysiology [editorial]. 
    American Journal of Respiratory and Critical Care Medicine.  202. 2020
  • Time to rethink the approach to treating acute respiratory distress syndrome [editorial]. 
    JAMA.  319. 2018
  • Volutrauma and atelectrauma: which is worse [editorial]?. 
    Critical Care (London, England).  22. 2018
  • Transpulmonary pressure meaning: Babel or conceptual evolution [editorial]?. 
    American Journal of Respiratory and Critical Care Medicine.  195. 2017
  • Prone positioning and neuromuscular blocking agents are part of standard care in severe ARDS patients: we are not sure [editorial]. 
    Intensive Care Medicine.  41. 2015
    • Review
  • The ventilator of the future: key principles and unmet needs [review]. 
    Critical Care (London, England). 2024
  • The physiological underpinnings of life-saving respiratory support [review]. 
    Intensive Care Medicine. 2022
  • COVID-19 pneumonia: pathophysiology and management [review]. 
    European Respiratory Review: An Official Journal of the European Respiratory Society. 2021
  • Improving lung compliance by external compression of the chest wall [review]. 
    Critical Care (London, England). 2021
  • Personalized mechanical ventilation in acute respiratory distress syndrome [review]. 
    Critical Care (London, England). 2021
  • Extracorporeal membrane oxygenation for respiratory failure [review]. 
    Anesthesiology. 2020
  • Prone position in ARDS patients: why, when, how and for whom [review]. 
    Intensive Care Medicine. 2020
  • Static and dynamic contributors to ventilator-induced lung injury in clinical practice. Pressure, energy, and power [review]. 
    American Journal of Respiratory and Critical Care Medicine. 2020
  • Respiratory support in patients with acute respiratory distress syndrome: an expert opinion [review]. 
    Critical Care (London, England). 2017
  • The future of mechanical ventilation: lessons from the present and the past [review]. 
    Critical Care (London, England). 2017
  • The intensive care medicine research agenda for airways, invasive and noninvasive mechanical ventilation [review]. 
    Intensive Care Medicine. 2017
  • The "baby lung" became an adult [review]. 
    Intensive Care Medicine. 2016
  • Our favorite unproven ideas for future critical care [review]. 
    Critical Care (London, England). 2013
  • Prone position in acute respiratory distress syndrome. Rationale, indications, and limits [review]. 
    American Journal of Respiratory and Critical Care Medicine. 2013
  • Propagation prevention: a complementary mechanism for "lung protective" ventilation in acute respiratory distress syndrome [review]. 
    Critical Care Medicine. 2008
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