Osteoporosis in a 60-year-old male with a history of chronic myeloid leukemia treated with imatinib mesylate
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Overview

abstract

  • Secondary osteoporosis is defined as a decline in bone mineral density due to any underlying etiology, which usually results in accelerated bone loss than expected for the individual's age or gender. Almost 50-80% of men diagnosed with osteoporosis have secondary osteoporosis. We present a case of a 60-year-old male with secondary osteoporosis with a history of imatinib mesylate-treated chronic myeloid leukemia (CML). Imatinib mesylate has revolutionized the management of individuals with chronic myeloid leukemia, which is now managed as a chronic disease. Imatinib has been demonstrated to cause dysregulation of bone metabolism. The long-term effects of imatinib on bone metabolism are still unknown.

  • Link to Article

    publication date

  • 2023
  • published in

  • Cureus  Journal
  • Research

    keywords

  • Drugs and Drug Therapy
  • Leukemia
  • Osteoporosis
  • Additional Document Info

    volume

  • 15
  • issue

  • 6