Jared M. Fine, PhD
Research Associate, Center for Memory & Aging

About

Education and training: PhD, physiology, University of Minnesota, Minneapolis; MS, University of Minnesota.

Overview/research interests: Development of intranasal drug-delivery technologies for the treatment of neurodegenerative diseases.

Current research activities and funding:

  • Efficacy and biochemical mechanisms of treatment with intranasal deferoxamine and insulin in models of Alzheimer’s and Parkinson’s disease
  • Mechanisms of delivery from the nasal cavity to the brain

Affiliation

positions

  • Research Associate, Neuroscience Research Centers 2006 -
  • Publications While At HealthPartners

    selected publications

    Journal Article
  • Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer's disease
    Frontiers in Neuroscience. 2025
  • Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non-disease-specific pathway of functional neurologic improvement
    Brain and behavior. 2020
  • Intranasal delivery of low-dose insulin ameliorates motor dysfunction and dopaminergic cell death in a 6-OHDA rat model of Parkinson's Disease
    Neuroscience Letters. 2020
  • Intranasal coadministration of a diazepam prodrug with a converting enzyme results in rapid absorption of diazepam in rats
    Journal of Pharmacology and Experimental Therapeutics. 2019
  • Quantifying intranasally administered deferoxamine in rat brain tissue with mass spectrometry
    ACS Chemical Neuroscience. 2019
  • Contact

    full name

  • Jared M. Fine, PhD
  • primary email

  • Jared.M.Fine@healthpartners.com
  • located in facility

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